Prof Oliver Howes will open the session with an overview of treatment resistance in psychiatry, considering its conceptualisation, its epidemiology, its impact, and some common neurobiological models. He will provide a structure to address treatment resistance, including research avenues to enable targeted and personalised therapeutic approaches. He will also present health and care outcomes from a secondary care treatment resistant psychosis service. · Prof James MacCabe will present his latest data on the factors influencing outcomes and continuation in people taking clozapine · Prof Mitul Mehta will talk to us about his work in Experimental Medicine – offering hope for the future of psychosis. Experimental medicine has the potential to provide causal evidence for biological theories and de-risk drug development, but is rarely deployed in psychiatry. This talk will demonstrate where experimental medicine models have been successful and highlight major challenges for this approach in psychiatry.
Chair: Professor Fiona Gaughran, South London and Maudsley NHS Foundation Trust and the Institute of Psychiatry, Psychology and Neuroscience, King’s College London
Treatment resistance in psychiatry - Professor Oliver Howes, Institute of Psychiatry, Psychology and Neuroscience, King's College London and South London and Maudsley NHS Foundation Trust
Should we prescribe clozapine in children? - Professor James MacCabe, National Psychosis Unit, South London and Maudsley NHS Foundation Trust and Institute of Psychiatry, Psychology and Neuroscience, King's College London
Experimental medicine models in psychosis - Professor Mitul Mehta, Institute of Psychiatry, Psychology and Neuroscience, King's College London
Prices
Non-Member: £34
Member: £23
Higher Trainees/SAS Doctors: £18
Core Trainees/Subsided*/Retired/Medical Students/FY Doctors: £12
