TrOn – Chromosomal abnormalities and inherited conditions in psychiatry

Dr Bronagh Sproule and reviewed by Dr William Howie

60 minutes

November 2021

TrOn learning module

TRON Chromosomal abnormalities.jpg

This module can be seen as covering two distinct areas of clinical genetics in psychiatry. The first half deals largely with inherited syndromes, and is concerned with clinical features and the modes of inheritance. The second half deals with the increasingly relevant and expanding field of inheritability in common psychiatric conditions. In some areas, such as familial-type Alzheimer’s disease, the genetic aetiology is becoming increasingly clear; in others, including the affective disorders and schizophrenia, recent genome-wide studies have served to illustrate the complexity of the genetics involved, and how much work is still to be done.

In any case, the module aims to provide a firm knowledge base in inherited syndromes, and an up-to-date summary of current research findings in genetics in common psychiatric conditions.


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