Author(s):Professor Grainne McAlonan
Duration:30 minutes
Credits:0.5
Published:June 2026
Type:Congress webinar 2026
Sensory distress experienced by over 90% of autistic people impacts education, employment, and healthcare; drives mental health problems; erodes Quality of Life; and contributes to €258 billion annual cost to the EU in lost productivity. A major priority for autistic people, by taking a neurodevelopmental perspective, we are making progress. Alterations in brain sensory systems at birth are upstream of broader autistic outcomes and studies in autistic adults confirm this arises from GABAergic imbalance but is restored by the GABAb receptor agonist, arbaclofen. Capturing individual arbaclofen responsivity brings hope for greater precision in sensory management and improved Quality of Life.
Professor Grainne McAlonan, NIHR Maudsley Biomedical Research Centre
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