In this symposium we will be showcasing how through the NIHR Mental Health Mission, a £42 million project aiming to build research infrastructure within the NHS, we have been advancing towards providing personalised care to patients with severe mental illness, including psychosis.
We will provide an overview of how 2,000 patients with early psychosis will be recruited and deeply phenotyped. This will be done by acquiring their electronic health records, obtaining their mental health data over time through the use of a purpose-built phone app, as well as by conventional means, through clinician-administered questionnaires. Participants will also give samples that will be analysed to obtain ‘omic phenotypes including exome sequencing and proteomics.
Our speakers, chaired by Prof Graham Murray, will provide:
- an overview of EPICARE, a national integrated digital registry and clinical decision support system, including how app-based psychiatric scales and live phenotype readings, can benefit research and participants
- a view of the future of clinical ‘omic phenotyping in psychiatry, with a case study on schizophrenia genetics
- information about how phenotyping individuals with early psychosis can have clinical benefit by providing tailored clinical care, focussing on risk prediction modelling.
The session will outline how research can directly benefit clinical practice, by:
- Developing digital systems that can directly improve patient care
- Providing more funding and better staffing clinical services
- Improving our knowledge of psychotic disorders; d) advancing personalised approaches to medicine
Learning objectives
This session will:
- Provide an overview of EPICARE, a national integrated digital registry and clinical decision support system
- Provide an overview of the Early Psychosis Mission, a national infrastructure programme advancing early intervention service research
- Present the potential clinical benefits of large-scale research projects in psychiatry.
Speakers
Chair: Professor Graham Murray, University of Cambridge, Cambridge
Professor Rachel Upthegrove, University of Oxford, Oxford
Dr Kimberley Kendall, University of Cardiff, Cardiff
Dr Emanuele F Osimo, University of Cambridge, Cambridge
Availability
This webinar is part of the Congress webinar 2025 package. If you attended all four days of Congress, you will have access to these as part of your Congress package. Otherwise the Congress webinar 2025 package can be purchased below.
